Our latest work entitled: "Adverse effects polystyrene microplastics exert on zebrafish heart – Molecular to individual level", has been recently published in Journal of Hazardous Materials (I.F. 9.038), April 2021.
Part of this work has conducted after financial support received through the research project “Intergovernmental International Scientific and Technological Innovation-Cooperation. Joint declaration of Science and Technology Cooperation between China and Greece” with the topic “Development of monitoring and removal strategies of emerging micro-pollutants in wastewaters” (Grant no: Τ7ΔΚΙ-00220).
Abstract
In the present study the effects of sublethal concentrations of polystyrene microplastics (PS-MPs) on zebrafish were evaluated at multiple levels, related to fish activity and oxidative stress, metabolic changes and contraction parameters in the heart tissue. Zebrafish were fed for 21 days food enriched with PS-MPs (particle sizes 3–12 µm) and a battery of stress indices like DNA damage, lipid peroxidation, autophagy, ubiquitin levels, caspases activation, metabolite adjustments, frequency and force of ventricular contraction were measured in fish heart, parallel to fish swimming velocity. In particular, exposure to PS-MPs caused significant decrease in heart function and swimming competence, while enhanced levels of oxidative stress indices and metabolic adjustments were observed in the heart of challenged species. Among stress indices, DNA damage was more vulnerable to the effect of PS-MPs. Our results provide evidence on the multiplicity of the PS-MPs effects on cellular function, physiology and metabolic pathways and heart rate of adult fish and subsequent effects on fish activity and fish fitness thus enlightening MPs characterization as a potent environmental pollutant.
Read the full text here.
Commentaires